BAM
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Three new FWO mandates starting at CMET
READ MORE: Three new FWO mandates starting at CMETHannah De Sutter Aquaculture loses billions annually due to bacterial diseases, with Vibrio species from the Harveyi clade among the most harmful pathogens. As antibiotics resistance increases, alternative approaches are being investigated, including antivirulence therapy: a strategy that disarms pathogens instead of killing them. My research focuses on the ToxR regulon, a virulence regulatory system in Vibrio spp. By using small-molecule…
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Spread of resistance to quorum sensing inhibition
READ MORE: Spread of resistance to quorum sensing inhibitionAntibiotic resistance is one of the major societal challenges of this moment. When targeting viability (e.g. with antibiotics), resistant cells have a very high fitness advantage over susceptible cells and as a consequence, resistance is spreading rapidly. Because of that, the BAM group at CMET (prof. Tom Defoirdt) is investigating another approach: targeting activity. One…